منابع مشابه
Shank Proteins Differentially Regulate Synaptic Transmission
Shank proteins, one of the principal scaffolds in the postsynaptic density (PSD) of the glutamatergic synapses, have been associated with autism spectrum disorders and neuropsychiatric diseases. However, it is not known whether different Shank family proteins have distinct functions in regulating synaptic transmission, and how they differ from other scaffold proteins in this aspect. Here, we in...
متن کاملSex Hormones and Their Receptors Regulate Liver Energy Homeostasis
The liver is one of the most essential organs involved in the regulation of energy homeostasis. Hepatic steatosis, a major manifestation of metabolic syndrome, is associated with imbalance between lipid formation and breakdown, glucose production and catabolism, and cholesterol synthesis and secretion. Epidemiological studies show sex difference in the prevalence in fatty liver disease and sugg...
متن کاملSex Hormones Regulate Cytoskeletal Proteins Involved in Brain Plasticity
In the brain of female mammals, including humans, a number of physiological and behavioral changes occur as a result of sex hormone exposure. Estradiol and progesterone regulate several brain functions, including learning and memory. Sex hormones contribute to shape the central nervous system by modulating the formation and turnover of the interconnections between neurons as well as controlling...
متن کاملSex hormones regulate hepatic fetuin expression in male and female rats.
BACKGROUND To date, there are limited studies on the sex-specific relationship between fetuins (Ft-A and Ft-B) and metabolic diseases. Our recent proteomic study has shown that fetuins may play sex-dependent roles in obesity and diabetes. In the present study, we investigated the expression of hepatic fetuins with respect to the effects of sex hormones both in vivo and in vitro. METHODS & RES...
متن کاملSex steroid hormones regulate constitutive expression of Cyp2e1 in female mouse liver.
CYP2E1 is of paramount toxicological significance because it metabolically activates a large number of low-molecular-weight toxicants and carcinogens. In this context, factors that interfere with Cyp2e1 regulation may critically affect xenobiotic toxicity and carcinogenicity. The aim of this study was to investigate the role of female steroid hormones in the regulation of CYP2E1, as estrogens a...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2018
ISSN: 1662-5099
DOI: 10.3389/fnmol.2018.00337